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A new therapy is showing success as a way to prevent COVID-19 symptoms in mice. Researchers have found that infecting the nasal passages of mice with the virus that causes COVID-19 led to a rapid, escalating attack on the brain that triggered severe illness, even after the lungs were successfully clearing themselves of the virus. Results from a new study suggest the immune systems of people infected with COVID-19 may rely on antibodies created during infections from earlier coronaviruses to help fight the disease. by Tianling Ou, Huihui Mou, Lizhou Zhang, Amrita Ojha, Hyeryun Choe, Michael FarzanHydroxychloroquine, used to treat malaria and some autoimmune disorders, potently inhibits viral infection of SARS coronavirus (SARS-CoV-1) and SARS-CoV-2 in cell-culture studies. However, human clinical trials of hydroxychloroquine[…] by Jee Youn Hwang, Unn Hwa Lee, Min Jin Heo, Min Sun Kim, Ji Min Jeong, So Yeon Kim, Mun Gyeong Kwon, Bo Young Jee, Ki Hong Kim, Chan-Il Park, Jeong Woo ParkViral hemorrhagic septicemia virus (VHSV) is a rhabdovirus[…] by Charline Bacchus-Souffan, Mark Fitch, Jori Symons, Mohamed Abdel-Mohsen, Daniel B. Reeves, Rebecca Hoh, Mars Stone, Joseph Hiatt, Peggy Kim, Abha Chopra, Haelee Ahn, Vanessa A. York, Daniel L. Cameron, Frederick M. Hecht, Jeffrey N. Martin, Steven A. Yukl, Simon[…] by Meztlli O. Gaytán, Anirudh K. Singh, Shireen A. Woodiga, Surina A. Patel, Seon-Sook An, Arturo Vera-Ponce de León, Sean McGrath, Anthony R. Miller, Jocelyn M. Bush, Mark van der Linden, Vincent Magrini, Richard K. Wilson, Todd Kitten, Samantha J.[…] by Jennifer Gribble, Laura J. Stevens, Maria L. Agostini, Jordan Anderson-Daniels, James D. Chappell, Xiaotao Lu, Andrea J. Pruijssers, Andrew L. Routh, Mark R. DenisonRecombination is proposed to be critical for coronavirus (CoV) diversity and emergence of SARS-CoV-2 and other[…] A study across New York City found that out-of-hospital sudden deaths follow the geographic distribution of SARS-CoV-2, suggesting an association between the two, investigators report. A new statistical model suggests that an infected student returning home for Christmas would, on average, have infected just less than one other household member.
Potential COVID-19 drug is successful in lab study
Virology News -- ScienceDailyJan 20, 2021 | 00:43 amStudy finds COVID-19 attack on brain, not lungs, triggers severe disease in mice
Virology News -- ScienceDailyJan 19, 2021 | 16:44 pmCOVID-19 virus triggers antibodies from previous coronavirus infections, study finds
Virology News -- ScienceDailyJan 19, 2021 | 16:43 pmHydroxychloroquine-mediated inhibition of SARS-CoV-2 entry is attenuated by TMPRSS2
PLOS Pathogens: New ArticlesJan 19, 2021 | 14:00 pmNaturally occurring substitution in one amino acid in VHSV phosphoprotein enhances viral virulence in flounder
PLOS Pathogens: New ArticlesJan 19, 2021 | 14:00 pmRelationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART
PLOS Pathogens: New ArticlesJan 19, 2021 | 14:00 pmA novel sialic acid-binding adhesin present in multiple species contributes to the pathogenesis of Infective endocarditis
PLOS Pathogens: New ArticlesJan 19, 2021 | 14:00 pmThe coronavirus proofreading exoribonuclease mediates extensive viral recombination
PLOS Pathogens: New ArticlesJan 19, 2021 | 14:00 pmWhere COVID-19 hit hardest, sudden deaths outside the hospital increased, study finds
Virology News -- ScienceDailyJan 18, 2021 | 16:31 pmStudents returning home may have caused 9,400 secondary COVID-19 infections across UK
Virology News -- ScienceDailyJan 18, 2021 | 15:35 pm
